Cell

Cell Miniature Mass Spectrometer

Delivering real-time solutions

Redefining the future of detection

Anytime

No pre-treatment required
Suitable for complex matrices
Support multiple application scenarios

Anywhere

Lightweight and portable
Removable internal battery
No external devices required

Anybody

Intelligent operation
Self-built spectrum library
Automatic calibration
5G networking

Miniaturization of MS Systems

20+ Years of miniature MS development

2006

Mini 10

10 kg

2008

Mini 11

4 kg

2012

BackpackMini

12 kg

2013

Mini 12

25 kg

2019

Mini β

22 kg

2021

Cell

8.5 kg

Quality Performance

Monitoring of hypertensive pharmaceutical drugs

Metabolite detection

Excellent sensitivity and resolution for rapid identification and detection of compounds in complex matrices.
Research and applications in various fields including medicine, food sciences, and organic synthesis.

Precise Quantitative Analysis

Features

Rapid Diagnosis of Brain Tumors by Onco-Metabolic Detection Using Miniature Mass Spectrometry

The diagnosis and treatment of brain tumors have long been challenging due to unique structure and function. Metabolic reprogramming brings the chances for rapid MS diagnosis of brain tumors.
The combination of ambient direct ionization and mini-MS broke the barriers of complex pretreatment and high cost of MS, enabling point-of-care MS analysis.

The workflow of rapid metabolic analysis of gliomas with miniature MS

S-plot diagram of metabolites to distinguish IDH mutant and wild-type

ROC curves obtained according to relative intensity of 2-HG alone or 2-HG/GLU ratios for IDH mutation

achieve a sensitivity, specificity, and accuracy of 100%

The intraoperative diagnosis of isocitrate dehydrogenase (IDH) mutation can be achieved in just 1.5 minutes
By monitoring the ratio of 2-hydroxyglutarate (2-HG) and glutamic acid (GLU) using mini-MS
More metabolic information can be provided
Provide a rapid diagnosis of brain tumors and genotypes
More sensitive, accurate and efficient

In 2024, PNAS published Rapid detection of lDH mutations in gliomas by intraoperative mass spectrometry, which suggest that MS could be used to identify lDH-mut tissue margins at locations of interest selected by the surgeon intraoperatively and rapidly within 2 min. The article also demonstrated that this molecular measurement should assist the surgeon in achieving optimal surgical resection of infiltrated tissue in those cases where the tumor core is lDH-mutant positive.

(A) Confusion matrix showing correlation between IHC and/or genetic testing and DCS-Mini MS assessments of IDH genotype from 156 core biopsies. Intraoperative analysis of IDH mutation by 2-HG/Glu achieved a sensitivity, speciffcity, and accuracy all of 100% by DCS-Mini MS. (B) Box plots demonstrating separation of IDH- wt and IDH- mut tumors by DCS-Mini MS measurements (***P < 0.0001). (C) ROC curves demonstrate perfect classiffcation of IDH- wt and mut tumors by 2-HG/Glu ratios irrespective of method.*

*PNAS, 2024,121(23),e2318843121

Course Design of Mass Spectrometry Experiments for High School and University

Mass spectrometry has been widely used in industry and scientific research due to its significant advantages in sensitivity, specificity and multi-parameter detection. However, it is difficult to obtain on-site experience, especially in tuning and building instruments, due to the high costs of instrument procurement, operation and training.
In order to provide practical mass spectrometry training for students，we have developed and designed a series of instrument laboratory courses on miniature mass spectrometers.